PUBLICATIONS
ARF4-mediated intracellular transport as a broad-spectrum antiviral target
Ming-Yuan Li, Kao Deng, Xiao-He Cheng, Lewis Yu-Lam Siu, Zhuo-Ran Gao, Trupti Shivaprasad Naik, Viktoriya G. Stancheva, Peter Pak-Hang Cheung, Qi-Wen Teo, Sophie W. van Leur, Ho-Him Wong, Yun Lan, Tommy Tsan-Yuk Lam, Meng-Xu Sun, Na-Na Zhang, Yue Zhang, Tian-Shu Cao, Fan Yang, Yong-Qiang Deng, Sumana Sanyal & Cheng-Feng Qin
Detection and characterisation of high pathogenicity avian influenza virus (H5N1/H5N8) clade 2.3.4.4b, Hong Kong SAR, China, 2021 to 2024
Wanying Sun, Ka Tim Choy, Ka Man Cheng, Christopher J Brackman, Samuel MS Cheng, Thomas HC Sit, Anne CN Tse, Leslie D Sims, Haogao Gu, Amy WY Tang, Andrew NC Wong, Andrew TL Tsang, Joe CT Koo, Leo LH Luk, Hui-Ling Yen, Malik Peris, Leo LM Poon
Differential antigenic imprinting effects between influenza H1N1 hemagglutinin and neuraminidase in a mouse model
Huibin Lv, Qi Wen Teo, Chang-Chun D Lee, Weiwen Liang, Danbi Choi, Kevin J Mao, Madison R Ardagh, Akshita B Gopal, Arjun Mehta, Matt Szlembarski, Roberto Bruzzone, Ian A Wilson, Nicholas C Wu, Chris K P Mok
Updated checklist with new records and molecular data for the mosquitoes (Diptera: Culicidae) of Hong Kong
Shaolin Han, Elliott F Miot, Yunshi Liao, Pradya Somboon, Ralph E Harbach, Ka Mei Sze-To, Lilia Tsz-Wing Tang, Benoit Guénard, Tommy Tsan-Yuk Lam
Antibody Fc receptor binding and T cell responses to homologous and heterologous immunization with inactivated or mRNA vaccines against SARS-CoV-2
Carolyn A. Cohen, Nancy H. L. Leung, Prathanporn Kaewpreedee, Kelly W. K. Lee, Janice Zhirong Jia, Alan W. L. Cheung, Samuel M. S. Cheng, Masashi Mori, Dennis K. M. Ip, Leo L. M. Poon, J. S. Malik Peiris, Benjamin J. Cowling & Sophie A. Valkenburg
A(H2N2) and A(H3N2) influenza pandemics elicited durable cross-reactive and protective antibodies against avian N2 neuraminidases
Zaolan Liang, Xia Lin, Lihong Sun, Kimberly M. Edwards, Wenjun Song, Hailiang Sun, Yanmin Xie, Fangmei Lin, Shiman Ling, Tingting Liang, Biying Xiao, Jiaqi Wang, Min Li, Chin-Yu Leung, Huachen Zhu, Nisha Bhandari, Raghavan Varadarajan, Min Z. Levine, Malik Peiris, Robert Webster, Vijaykrishna Dhanasekaran, Nancy H. L. Leung, Benjamin J. Cowling, Richard J. Webby, Mariette Ducatez, Mark Zanin & Sook-San Wong
Epistasis mediates the evolution of the receptor binding mode in recent human H3N2 hemagglutinin
Ruipeng Lei, Weiwen Liang, Wenhao O. Ouyang, Andrea Hernandez Garcia, Chika Kikuchi, Shengyang Wang, Ryan McBride, Timothy J. C. Tan, Yuanxin Sun, Chunke Chen, Claire S. Graham, Lucia A. Rodriguez, Ivana R. Shen, Danbi Choi, Roberto Bruzzone, James C. Paulson, Satish K. Nair, Chris K. P. Mok & Nicholas C. Wu
Influenza antibody breadth and effector functions are immune correlates from acquisition of pandemic infection of children
Janice Z. Jia, Carolyn A. Cohen, Haogao Gu, Milla R. McLean, Raghavan Varadarajan, Nisha Bhandari, Malik Peiris, Gabriel M. Leung, Leo L. M. Poon, Tim Tsang, Amy W. Chung, Benjamin J. Cowling, Nancy H. L. Leung & Sophie A. Valkenburg
Amino acids in the polymerase complex of shorebird-isolated H1N1 influenza virus impact replication and host-virus interactions in mammalian models
Yaqin Bai, Hui Lei, Wenjun Song, Sang-Chul Shin, Jiaqi Wang, Biying Xiao, Zeynep A Koçer, Min-Suk Song, Robert Webster, Richard J Webby, Sook-San Wong, Mark Zanin
Stability of SARS-CoV-2 on Commercial Aircraft Interior Surfaces with Implications for Effective Control Measures
Kenrie P Y Hui, Alex W H Chin, John Ehret, Ka-Chun Ng, Malik Peiris, Leo L M Poon, Karen H M Wong, Michael C W Chan, Ian Hosegood, John M Nicholls
Dissecting human population variation in single-cell responses to SARS-CoV-2
Yann Aquino, Aurélie Bisiaux, Zhi Li, Mary O’Neill, Javier Mendoza-Revilla, Sarah Hélène Merkling, Gaspard Kerner, Milena Hasan, Valentina Libri, Vincent Bondet, Nikaïa Smith, Camille de Cevins, Mickaël Ménager, Francesca Luca, Roger Pique-Regi, Giovanna Barba-Spaeth, Stefano Pietropaoli, Olivier Schwartz, Geert Leroux-Roels, Cheuk-Kwong Lee, Kathy Leung, Joseph T. Wu, Malik Peiris, Roberto Bruzzone, Laurent Abel, Jean-Laurent Casanova, Sophie A. Valkenburg, Darragh Duffy, Etienne Patin, Maxime Rotival, Lluis Quintana-Murci
Comparative antibody and cell-mediated immune responses, reactogenicity, and efficacy of homologous and heterologous boosting with CoronaVac and BNT162b2 (Cobovax): an open-label, randomised trial
Nancy H L Leung, Samuel M S Cheng, Carolyn A Cohen, Mario Martín-Sánchez, Niki Y M Au, Leo L H Luk, Leo C H Tsang, Kelvin K H Kwan, Sara Chaothai, Lison W C Fung, Alan W L Cheung, Karl C K Chan, John K C Li, Yvonne Y Ng, Prathanporn Kaewpreedee, Janice Z Jia, Dennis K M Ip, Leo L M Poon, Gabriel M Leung, J S Malik Peiris, Sophie A Valkenburg, Benjamin J Cowling
Broad-spectrum pan-genus and pan-family virus vaccines
Chee Wah Tan, Sophie A Valkenburg, Leo L M Poon, Lin-Fa Wang
SARS-CoV-2 infection aggravates cigarette smoke-exposed cell damage in primary human airway epithelia
Rui Chen, Kenrie Pui-Yan Hui, Yingmin Liang, Ka-Chun Ng, John Malcolm Nicholls, Mary Sau-Man Ip, Malik Peiris, Michael Chi-Wai Chan, Judith Choi-Wo Mak
Resurgence of Omicron BA.2 in SARS-CoV-2 infection-naive Hong Kong
Ruopeng Xie, Kimberly M Edwards, Dillon C Adam, Kathy S M Leung, Tim K Tsang, Shreya Gurung, Weijia Xiong, Xiaoman Wei, Daisy Y M Ng, Gigi Y Z Liu, Pavithra Krishnan, Lydia D J Chang, Samuel M S Cheng, Haogao Gu, Gilman K H Siu, Joseph T Wu, Gabriel M Leung, Malik Peiris, Benjamin J Cowling, Leo L M Poon, Vijaykrishna Dhanasekaran
Replication of Novel Zoonotic-Like Influenza A(H3N8) Virus in Ex Vivo Human Bronchus and Lung
Kenrie P Y Hui, John C W Ho, Ka-Chun Ng, Samuel M S Cheng, Ko-Yung Sit, Timmy W K Au, Leo L M Poon, John M Nicholls, Malik Peiris, Michael C W Chan
Within-host genetic diversity of SARS-CoV-2 lineages in unvaccinated and vaccinated individuals
Haogao Gu, Ahmed Abdul Quadeer, Pavithra Krishnan, Daisy Y M Ng, Lydia D J Chang, Gigi Y Z Liu, Samuel M S Cheng, Tommy T Y Lam, Malik Peiris, Matthew R McKay, Leo L M Poon
Risk of within-hotel transmission of SARS-CoV-2 during on-arrival quarantine in Hong Kong: an epidemiological and phylogenomic investigation
Dillon C. Adam, Mario Martín-Sánchez, Haogao Gu, Bingyi Yang, Yun Lin, Peng Wu, Eric H.Y. Lau, Gabriel M. Leung, Leo L.M. Poon, Benjamin J. Cowling
Viral burden rebound in hospitalised patients with COVID-19 receiving oral antivirals in Hong Kong: a population-wide retrospective cohort study
Carlos K H Wong, Kristy T K Lau, Ivan C H Au, Eric H Y Lau, Leo L M Poon, Ivan F N Hung, Benjamin J Cowling, Gabriel M Leung
Real-world COVID-19 vaccine effectiveness against the Omicron BA.2 variant in a SARS-CoV-2 infection-naive population
Jonathan J Lau, Samuel M S Cheng, Kathy Leung, Cheuk Kwong Lee, Asmaa Hachim, Leo C H Tsang, Kenny W H Yam, Sara Chaothai, Kelvin K H Kwan, Zacary Y H Chai, Tiffany H K Lo, Masashi Mori, Chao Wu, Sophie A Valkenburg, Gaya K Amarasinghe, Eric H Y Lau, David S C Hui, Gabriel M Leung, Malik Peiris, Joseph T Wu
Development of multiplex RT-ddPCR assays for detection of SARS-CoV-2 and other respiratory viruses
Nathaniel K. C. Leong, Haogao Gu, Daisy Y. M. Ng, Lydia D. J. Chang, Pavithra Krishnan, Samuel S. M. Cheng, Malik Peiris, Leo L. M. Poon
Slow Waning of Antibodies Following BNT162b2 as a Third Dose in Adults Who Had Previously Received 2 Doses of Inactivated Vaccine
Benjamin J Cowling, Samuel M S Cheng, Mario Martín-Sánchez, Niki Y M Au, Karl C K Chan, John K C Li, Lison W C Fung, Leo L H Luk, Leo C H Tsang, Dennis K M Ip, Leo L M Poon, Gabriel M Leung, J S Malik Peiris, Nancy H L Leung
Priming conditions shape breadth of neutralizing antibody responses to sarbecoviruses
Janice Zhirong Jia, Chee Wah Tan, Samuel M. S. Cheng, Haogao Gu, Aileen Ying Yan Yeoh, Chris Ka Pun Mok, Yanqun Wang, Jincun Zhao, Nancy H. L. Leung, Benjamin J. Cowling, Leo L. M. Poon, David S. C. Hui, Linfa Wang, Malik Peiris & Sophie A. Valkenburg
Immunogenicity and reactogenicity of SARS-CoV-2 vaccines BNT162b2 and CoronaVac in healthy adolescents
Jaime S Rosa Duque, Xiwei Wang, Daniel Leung, Samuel M S Cheng, Carolyn A Cohen, Xiaofeng Mu, Asmaa Hachim, Yanmei Zhang, Sau Man Chan, Sara Chaothai, Kelvin K H Kwan, Karl C K Chan, John K C Li, Leo L H Luk, Leo C H Tsang, Wilfred H S Wong, Cheuk Hei Cheang, Timothy K Hung, Jennifer H Y Lam, Gilbert T Chua, Winnie W Y Tso, Patrick Ip, Masashi Mori, Niloufar Kavian, Wing Hang Leung, Sophie Valkenburg, Malik Peiris, Wenwei Tu, Yu Lung Lau
Strength and durability of antibody responses to BNT162b2 and CoronaVac
Benjamin J Cowling, Irene O L Wong, Eunice Y C Shiu, Amber Y T Lai, Samuel M S Cheng, Sara Chaothai, Kelvin K H Kwan, Mario Martín-Sánchez, Leo L M Poon, Dennis K M Ip, Gabriel M Leung, Nancy H L Leung, J S Malik Peiris
Natural Reassortment of Eurasian Avian-Like Swine H1N1 and Avian H9N2 Influenza Viruses in Pigs, China
Wanying Sun, Samuel S M Cheng, Kristy N T Lam, Tsz C Kwan, Ricky W K Wong, Leo H K Lau, Gigi Y Z Liu, Leo L H Luk, John K C Li, Haogao Gu, Malik Peiris, Leo L M Poon
SARS-CoV-2 Omicron variant BA.2 neutralisation in sera of people with Comirnaty or CoronaVac vaccination, infection or breakthrough infection, Hong Kong, 2020 to 2022
Samuel MS Cheng, Chris Ka Pun Mok, Karl CK Chan, Susanna S Ng, Bosco HS Lam, Leo LH Luk, Fanny W Ko, Chunke Chen, Karen Yiu, John KC Li, Ken KP Chan, Leo CH Tsang, Leo LM Poon, David SC Hui, Malik Peiris
Recombinant BA.1/BA.2 SARS-CoV-2 Virus in Arriving Travelers, Hong Kong, February 2022
Haogao Gu, Daisy Y M Ng, Gigi Y Z Liu, Samuel S M Cheng, Pavithra Krishnan, Lydia D J Chang, Sammi S Y Cheuk, Mani M Y Hui, Tommy T Y Lam, Malik Peiris, Leo L M Poon
SARS-CoV-2 Omicron variant is more stable than the ancestral strain on various surfaces
Alex Wing Hong Chin, Alison Man Yuk Lai, Malik Peiris, Leo Lit Man Poon
Transmission of SARS-CoV-2 delta variant (AY.127) from pet hamsters to humans, leading to onward human-to-human transmission: a case study
Hui-Ling Yen, PhD, Thomas H C Sit, BVSc, Christopher J Brackman, BVSc, Shirley S Y Chuk, BVSc, Haogao Gu, PhD, Karina W S Tam, DVM, Pierra Y T Law, PhD, Prof Gabriel M Leung, MD, Prof Malik Peiris, FRCP, Prof Leo L M Poon, DPhil
Exploring the landscape of immune responses to influenza infection and vaccination
Sophie A. Valkenburg, Leo L. M. Poon
Transparent Anti-SARS-CoV-2 and Antibacterial Silver Oxide Coatings
Mohsen Hosseini, Alex W H Chin, Myra D Williams, Saeed Behzadinasab, Joseph O Falkinham, Leo L M Poon, William A Ducker
Genomic epidemiology of SARS-CoV-2 under an elimination strategy in Hong Kong
Haogao Gu, Ruopeng Xie, Dillon C. Adam, Joseph L.-H. Tsui, Daniel K. Chu, Lydia D. J. Chang, Sammi S. Y. Cheuk, Shreya Gurung, Pavithra Krishnan, Daisy Y. M. Ng, Gigi Y. Z. Liu, Carrie K. C. Wan, Samuel S. M. Cheng, Kimberly M. Edwards, Kathy S. M. Leung, Joseph T. Wu, Dominic N. C. Tsang, Gabriel M. Leung, Benjamin J. Cowling, Malik Peiris, Tommy T. Y. Lam, Vijaykrishna Dhanasekaran & Leo L. M. Poon
SARS-CoV-2 Omicron Variant Replication in Human Bronchus and Lung Ex Vivo
Kenrie P. Y. Hui, John C. W. Ho, Man-chun Cheung, Ka-chun Ng, Rachel H. H. Ching, Ka-ling Lai, Tonia Tong Kam, Haogao Gu, Ko-Yung Sit, Michael K. Y. Hsin, Timmy W. K. Au, Leo L. M. Poon, Malik Peiris, John M. Nicholls & Michael C. W. Chan
Neutralizing antibodies against the SARS-CoV-2 Omicron variant following homologous and heterologous CoronaVac or BNT162b2 vaccination
Samuel M. S. Cheng, Chris Ka Pun Mok, Yonna W. Y. Leung, Susanna S. Ng, Karl C. K. Chan, Fanny W. Ko, Chunke Chen, Karen Yiu, Bosco H. S. Lam, Eric H. Y. Lau, Ken K. P. Chan, Leo L. H. Luk, John K. C. Li, Leo C. H. Tsang, Leo L. M. Poon, David S. C. Hui, Malik Peiris
A Push for Real Normal: Mass Screening for COVID-19
Leo L M Poon
Reduction of Infectivity of SARS-CoV-2 by Zinc Oxide Coatings
Mohsen Hosseini, Saeed Behzadinasab, Alex W H Chin, Leo L M Poon, William A Ducker
ACS Biomater Sci Eng. 2021 Oct 6. doi: 10.1021/acsbiomaterials.1c01076. PMID: 34613703
Comparative immunogenicity of mRNA and inactivated vaccines against COVID-19
Wey Wen Lim, Loretta Mak, Gabriel M Leung, Benjamin J Cowling, Malik Peiris
Air travel-related outbreak of multiple SARS-CoV-2 variants
Vijaykrishna Dhanasekaran, Kimberly M Edwards, Ruopeng Xie, Haogao Gu, Dillon C Adam, Lydia D J Chang, Sammi S Y Cheuk, Shreya Gurung, Pavithra Krishnan, Daisy Y M Ng, Gigi Y Z Liu, Carrie K C Wan, Samuel S M Cheng, Dominic N C Tsang, Benjamin J Cowling, Malik Peiris, Leo L M Poon
Role of Epithelial-Endothelial Cell Interaction in the Pathogenesis of SARS-CoV-2 Infection
Simeprevir Potently Suppresses SARS-CoV-2 Replication and Synergizes with Remdesivir
Ho Sing Lo, Kenrie Pui Yan Hui, Hei-Ming Lai, Xu He, Khadija Shahed Khan, Simranjeet Kaur, Junzhe Huang,Zhongqi Li, Anthony K. N. Chan, Hayley Hei-Yin Cheung, Ka-Chun Ng, John Chi Wang Ho, Yu Wai Chen, Bowen Ma, Peter Man-Hin Cheung, Donghyuk Shin, Kaidao Wang, Meng-Hsuan Lee, Barbara Selisko, Cecilia Eydoux, Jean-Claude Guillemot, Bruno Canard, Kuen-Phon Wu, Po-Huang Liang, Ivan Dikic, Zhong Zuo, Francis K. L. Chan, David S. C. Hui, Vincent C. T. Mok, Kam-Bo Wong, Chris Ka Pun Mok, Ho Ko, Wei Shen Aik, Michael Chi Wai Chan, and Wai-Lung Ng