New publication in npj Vaccines from C2i's Managing Director Professor Leo Poon's team describing an innovative approach to developing a live attenuated SARS-CoV-2 vaccine candidate. The study demonstrates a novel approach to engineering a highly attenuated yet fully immunogenic SARS-CoV-2 vaccine candidate, showing: Near-sterile immunity in mice under stringent challenge conditions Broad protection against antigenically distinct variants and even SARS-CoV Complete block of o

Congratulations to our spin-off company C2iTech Limited for making the Top 5 of the EQT Impact Challenge Hong Kong 2026! C2iTech has officially reached the Top 5 of the EQT Impact Challenge Hong Kong 2026! Our innovative flight simulator for human respiratory drug response is changing the game. Support our journey to the Grand Finale — vote by 26 August: https://eqtimpactchallenge2026.scmp.com/

This week, we were delighted to welcome seven students from the Canadian International School of Hong Kong and St. Mary's Canossian College to C2i as part of the Asian Medical Students'​ Association Hong Kong (AMSAHK) Academic Research Competition 2025-26. Throughout the day, the students got a glimpse into life in a research institute, learning about some of our work in immunology, infectious diseases, vaccine development, and new therapeutic approaches. In addition to labor

Job reference number: C2i132-RP1 The Centre for Immunology & Infection (C2i) is a premier research institute focused on advancing biomarker discovery and the development of next-generation vaccines and therapeutic strategies. Founded through a strategic partnership of over 20 years between the LKS Faculty of Medicine at the University of Hong Kong (HKUMed) and the Institut Pasteur in Paris, C2i integrates world-class expertise in biomedical science to drive innovation in publ

Job Reference Number: C2i129-RP3 The Centre for Immunology & Infection (C2i) uses novel technology platforms for biomarker discovery and the development of new vaccine and therapeutic strategies. It is the fruit of a long-standing partnership of more than 20 years between the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) and the Institut Pasteur, Paris, two major international leaders combining their expertise to establish this centre of excellence. C2i

Job Reference Number: C2i130-RP3 The Centre for Immunology & Infection (C2i) uses novel technology platforms for biomarker discovery and the development of new vaccine and therapeutic strategies. It is the fruit of a long-standing partnership of more than 20 years between the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) and the Institut Pasteur, Paris, two major international leaders combining their expertise to establish this centre of excellence. C2i aims

Variability in the TLR3–type I interferon pathway before vaccination is associated with the strength of T‑cell responses following mRNA COVID‑19 vaccination. The InnoHK Centre for Immunology & Infection (InnoHK C2i), established through a strategic partnership between The University of Hong Kong (HKU) and the Institut Pasteur, together with collaborators from Milieu Interieur (Institut Pasteur), the Department of Paediatrics and Adolescent Medicine (HKU), the School of Publi

Job Reference Number: C2i-128-RP4 The Centre for Immunology & Infection (C2i) uses novel technology platforms for biomarker discovery and the development of new vaccine and therapeutic strategies. It is the fruit of a long-standing partnership of more than 20 years between the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) and the Institut Pasteur, Paris, two major international leaders combining their expertise to establish this centre of excellence. C

Job Reference Number: C2i-127-Admin The Centre for Immunology & Infection (C2i) uses novel technology platforms for biomarker discovery and the development of new vaccine and therapeutic strategies. It is the fruit of a long-standing partnership of more than 20 years between the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) and the Institut Pasteur, Paris - two major international leaders combining their expertise to establish this centre of excellence.

The Healthy Human Global Project - Hong Kong : a community-based cross-sectional study of a healthy Asian population The InnoHK Centre for Immunology & Infection (InnoHK C2i), established through a strategic partnership between The University of Hong Kong (HKU) and the Institut Pasteur, together with the Institut Pasteur Milieu Interieur (MI) , FAMILY Cohort (HKU, School of Public Health) and the Centre for Sports and Exercise (HKU CSE) have established the Healthy Hum

The Centre for Immunology & Infection is pleased to present the new edition of the Immunology Course, co‑organised with the HKU‑Pasteur Research Pole. Quantitative Immunology: From population to individual immunity NOVEMBER 15-20, 2026 Deadline for applications: 30 June 2026 The 12th HKU-Pasteur Immunology Course will explore the frontiers of quantitative immunology to describe the function of the immune system in health and disease at a population and individual level. This

A new publication in Nature Lab Animal from C2i’s Alex Chin and Leo Poon demonstrates that the emerging SARS‑CoV‑2 Omicron EG.5 and JN.1 variants induce enhanced pathogenicity in K18‑hACE2 mice, overcoming limitations of early Omicron models and enabling more robust preclinical assessment of vaccines and antivirals. Abstract : The reduced pathogenicity of early SARS-CoV-2 Omicron subvariants in human ACE2-expressing K18-hACE2 mice has posed challenges for assessing vacci

Join us on Thursday 26 March for a seminar from Professor Zhiyong Xi , Michigan State University. Registration: https://docs.google.com/forms/d/e/1FAIpQLSc8nEWPEZFIQ_VUwP_F8IT1KSPwekNIE0shPrsyJ0COcLcy6w/viewform

Job Reference Number: C2i-126-Admin The Centre for Immunology & Infection (C2i) uses novel technology platforms for biomarker discovery and the development of new vaccine and therapeutic strategies. It is the fruit of a long-standing partnership of more than 20 years between the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) and the Institut Pasteur, Paris, two major international leaders combining their expertise to establish this centre of excellence. C2i a

Reference Number: C2i125-RP2 The Centre for Immunology & Infection (C2i) uses novel technology platforms for biomarker discovery and the development of new vaccine and therapeutic strategies. It is the fruit of a long-standing partnership of more than 20 years between the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) and the Institut Pasteur, Paris, two major international leaders combining their expertise to establish this centre of excellence. C2i aims

The vaccine not only prevents severe disease, but also effectively blocks viral transmission in animal models, offering a promising strategy for pandemic preparedness against future coronavirus threats. A research team at the LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has developed a novel live-attenuated vaccine candidate, cb1, capable of generating broad immunity against a wide range of beta-coronaviruses with a single intranasal dose. The vaccine not on

Job Reference Number: C2i124-RP1 The Centre for Immunology & Infection (C2i) is a premier research institute focused on advancing biomarker discovery and the development of next-generation vaccines and therapeutic strategies. Founded through a strategic partnership of over 20 years between the LKS Faculty of Medicine at the University of Hong Kong (HKUMed) and the Institut Pasteur in Paris, C2i integrates world-class expertise in biomedical science to drive innovation in pub

Job Reference Number: C2i123-RP3 The Centre for Immunology & Infection (C2i) uses novel technology platforms for biomarker discovery and the development of new vaccine and therapeutic strategies. It is the fruit of a long-standing partnership of more than 20 years between the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) and the Institut Pasteur, Paris, two major international leaders combining their expertise to establish this centre of excellence. C2i

Job Reference Number: C2i122-Admin The Centre for Immunology & Infection Limited (C2i) is a premier research institute focused on advancing biomarker discovery and the development of next-generation vaccines and therapeutic strategies. Founded through a strategic partnership of over 20 years between the LKS Faculty of Medicine at the University of Hong Kong (HKUMed) and the Institut Pasteur in Paris, C2i integrates world-class expertise in biomedical science to drive innovati

Job Reference Number: C2i121-RP4 The Centre for Immunology & Infection (C2i) uses novel technology platforms for biomarker discovery and the development of new vaccine and therapeutic strategies. It is the fruit of a long-standing partnership of more than 20 years between the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) and the Institut Pasteur, Paris, two major international leaders combining their expertise to establish this centre of excellence. C2i