Natural Reassortment of Eurasian Avian-Like Swine H1N1 and Avian H9N2 Influenza Viruses in Pigs

Published in Emerging Infectious Diseases, a study led by Prof. Leo Poon and Prof. Malik Peiris, from HKU-Pasteur Research Pole and C2i, over swine influenza A viruses (IAVs) suggested that H9N2 viruses are infecting pigs and reassorting with swine influenza viruses in China.

Abstract:

Several zoonotic influenza A viruses detected in humans contain genes derived from avian H9N2 subtypes. We uncovered a Eurasian avian-like H1N1 swine influenza virus with polymerase basic 1 and matrix gene segments derived from the H9N2 subtype, suggesting that H9N2 viruses are infecting pigs and reassorting with swine influenza viruses in China.

>>> Natural Reassortment of Eurasian Avian-Like Swine H1N1 and Avian H9N2 Influenza Viruses in Pigs

Figure. Phylogenetic tree of polymerase basic 1 (A) and matrix (B) gene sequences of swine influenza viruses from China and reference sequences. Bold indicates human H7N9 and H10N8 sequences. (more)